2020年欧洲肿瘤内科学会亚洲峰会(ESMO ASIA)年会将采用线上虚拟会议的形式,于11月20-22日隆重召开。医脉通特梳理了乳腺癌领域口头报告专场和迷你口头报告专场的重磅研究,与您分享!

HR+/HER2-乳腺癌

monarchE研究更新:亚洲患者更适合接受辅助治疗!

CompLEEment-1研究亚洲亚组结果出炉

MONARCH 2东亚地区患者总生存期(OS)结果出炉

三阴性乳腺癌(TNBC)

Mpassion031研究到达主要终点

IMpassion130最终OS结果

KEYNOTE-522亚洲亚组:帕博利珠单抗+化疗(新)辅助治疗使TNBC患者pCR率达到59%

KEYNOTE-355亚洲亚组数据出炉,免疫联合治疗延长TNBC患者中位PFS最长达11.7个月

KEYNOTE-119亚太地区结果:免疫治疗单挑TNBC失利!

参考文献

LBA1 - Baseline characteristics of patients from Asia enrolled in monarchE, evaluating abemaciclib in high risk early breast cancer (ID 510) .2020 ESMO AISA

48MO - Ribociclib (RIB) + letrozole (LET) in Asian patients (pts) with hormone receptor-positive (HR+), human epidermal growth factor receptor-2–negative (HER2−) advanced breast cancer (ABC): Subgroup analysis of the phase IIIb CompLEEment-1 trial (ID 289) .2020 ESMO AISA

3MO - IMpassion031: Results from a phase III study of neoadjuvant (neoadj) atezolizumab + chemo in early triple-negative breast cancer (TNBC) (ID 512) .2020 ESMO AISA

49MO - IMpassion130: Final OS analysis from the pivotal phase III study of atezolizumab + nab-paclitaxel vs placebo + nab-paclitaxel in previously untreated locally advanced or metastatic triple-negative breast cancer (ID 511) .2020 ESMO AISA

1O - KEYNOTE-522 Asian subgroup: Phase III study of neoadjuvant pembrolizumab (pembro) vs placebo (pbo) + chemotherapy (chemo) followed by adjuvant pembro vs pbo for early triple-negative breast cancer (TNBC) (ID 656) .2020 ESMO AISA

43O - Phase III KEYNOTE-355 study of pembrolizumab (pembro) vs placebo (pbo) + chemotherapy (chemo) for previously untreated locally recurrent inoperable or metastatic triple-negative breast cancer (TNBC): Results for patients (Pts) enrolled in Asia (ID 659) .2020 ESMO AISA

44O - Pembrolizumab (pembro) vs chemotherapy (chemo) for previously treated metastatic triple-negative breast cancer (mTNBC): KEYNOTE-119 Asia-Pacific subpopulation (ID 645) .2020 ESMO AISA

45O - Abemaciclib plus fulvestrant in East Asian women with HR+, HER2- advanced breast cancer: Overall survival from MONARCH 2 (ID 284) .2020 ESMO AISA